In addition to celebrating the outstanding achievements in filmmaking, another major talking point of the Oscars was the performers’ remarkable body transformations, which many have attributed toOzempic.
Though it’s only been FDA-approved for treating Type 2 diabetes, the medication is often prescribed off-label for weight loss, as it suppresses appetite and contributes to a feeling of fullness.
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Celebrities stunned the internet with their drastic weight loss transformations at the Oscars
Image credits:Oscars
Among the celebrities rumored to have used Ozempic is Ariana Grande, nominated for Best Supporting Actress for her role inWicked.
The singer and actress opted for a strapless Schiaparelli gown that drew attention to her slender shoulders and arms.
Ariana’s svelte figure previously sparked concerns among fans during herWickedpromo tour, with many suggesting that her noticeable weight loss transformation was compromising her health.
Ariana Grande’s red carpet appearance reignited concerns about her health
Image credits:Gregg DeGuire/Penske Media
“Ariana Grande is so skinny I’m surprised she doesn’t disappear. It’s so sad she looked better before,” one fan wrote in reaction to her red-carpet pictures.
“I wish Ariana Grande would leave theOzempicalone,” another said.
“For real tho. Is Ariana Grande OK? She is so thin and talks so slowly now. I’m actually worried,” a third fan added.
ariana grande at the#Oscars(4k)pic.twitter.com/b0Nxrdty40
— ariana grande gifs (@vodolove)March 2, 2025
Image credits:vodolove
In 2023, Arianapublicly commentedon fans’ concerns over her weight, saying on TikTok that what some people considered her “healthiest” body was far from it.
“The body that you’ve been comparing my current body to was the unhealthiest version of my body.
“I was on a lot of antidepressants, and drinking on them, and eating poorly, and at the lowest point of my life when I looked the way you consider my healthy, but that, in fact, wasn’t my healthy.”
Cynthia Erivo’s one-shoulder dress highlighted her collarbones and slender arms
Image credits:John Shearer/97th Oscars/The Academy
Ariana’sWickedco-star,Cynthia Erivo, also raised speculation about her possibly taking Ozempic to look slim.
Cynthia has never confirmed whether she’s taken the semaglutide medication.
Demi Moore wore a fitted, glittery gown that accentuated her slim frame
Image credits:Amy Sussman/Getty Images
Another actress who sparked health concerns over her slim figure was Demi Moore, who was nominated for Best Actress forThe Substance. Demi donned a fitted Armani Privé gown that accentuated her slender frame.
“OMG, Demi Moore’s arm! Stop the Ozempic,” one netizen commented.
Demi previously opened up about her obsession over her appearance, sharing in her 2019 memoir, “[I was] dieting and exercising in a very obsessive-compulsive way… I changed my body over multiple times but wasn’t really myself.”
While filming theOscar-nominatedfilm, the 62-year-old star contracted shingles, a painful rash illness she said made her lose 20 pounds (approx. 9 kg).
Demi Moore at the#Oscarspic.twitter.com/V23hgfVbgh
— Variety (@Variety)March 2, 2025
Image credits:Variety
TheGhostactress revealed last September that she was able to become more flexible with her exercise regime and accept her “natural size.”
“After I finishedG.I. Janeis when I had a huge shift, because I had manipulated my body, I had changed it multiple times, through just pure force and discipline, and when I finished that film, I was so kind of worn down in this battle that I had been in that I finally surrendered,” she toldThe New York Times.
“I just started to ask to be my natural size because I didn’t know what it was. I literally couldn’t go to a gym. I couldn’t control food in that way.”
Georgina Chapman’s look also reignited rumors about Ozempic
Image credits:Frazer Harrison/WireImage
Other stars who appeared noticeably slimmer includeMindy Kaling, who revealed she dropped 40 lbs (approx. 18 kg) in 2023, and Georgina Chapman, who attended the ceremony to support her boyfriend, Adrien Brody, and has also been the subject of health concerns. Neither of them has addressed speculation about Ozempic.
While Mindy said she runs 20 miles (approx. 32 km) each week and weight lifts with her trainer, Georgina starts her day with a workout or a yoga session five or six times a week and does body sculpting.
“I tried a juice cleanse once and lasted about 12 hours. I thought I was going to die—I need food!” Georgina toldHarper’s Bazaar.
“My favorite cuisine is Italian; I love the simplicity and freshness. I eat a lot of fish and poultry, but I haven’t touched red meat since I was 18.”
Mindy Kaling revealed she dropped 40 lbs (approx. 18 kg) in 2023
Image credits:Neilson Barnard/Getty Images
Mindy Kaling poses for photos at the#Oscars.https://t.co/HxIBUAMCJlpic.twitter.com/JQL0jmmtle
Addressing the commentary that she looked “boney” in avideoposted last October, the actress and dancer said she’s never “been healthier.”
“I was full of inflammation in my 20’s and had a marker for an autoimmune that I addressed and committed to over a year and a half ago. I’ve frozen my eggs over the last few years which also shifts the body fluctuation,” Julianne shared.
“I’ve never been healthier or happier from the inside out. Grief, loss. Sadness and fear also get stored in the body and we hold on to that in different ways.
“I made it a huge priority to accept, express, process, and release a lot of emotions over the years.”
Julianne created her own fitness app, Kinrgy. To maintain her health, she drinks protein shakes and eats grilled chicken or salmon with veggies for dinner.
Selena Gomez attributed her weight fluctuations to her lupus medication
Selena Gomez at the#Oscarspic.twitter.com/85LlTbI4qG
Though some attributed Selena Gomez’s drastic weight loss to Ozempic, theEmilia Pérezactresssharedthat her weight fluctuations are due to her lupus medication, which causes water retention.
Lupus is a disease that causes the body’s immune system attack its own tissues and organs.
“When I’m taking [the medicine], I tend to hold a lot of water weight, and that happens very normally. And then when I’m off of it, I tend to kind of lose weight,” the Texas native said.
“My weight would constantly fluctuate because I would be on certain medications,” sheadded. “And obviously, people just ran with it. It was like they couldn’t wait to find a thing to bring me down. I was being shamed for gaining weight because of my lupus.”
Whoopi Goldberg revealed she took Mounjaro, a diabetes medication used for weight loss
Image credits:Earl Gibson III/Penske Media
Whoopi Goldberg, who presented the tribute to Quincy Jones alongsideOprah Winfrey, also drew attention to her weight-loss transformation.
“Oprah and Whoopi being a walking billboard for Ozempic,” one viewer commented, while another said, “My mother just referred to Whoopi Goldberg as Miss Ozempic.”
“Whoopi and Oprah serving Ozempic opulence,” a separate viewer added.
Image credits:ABC
TheSister Actstarrevealed that she started taking Mounjaro, another diabetes medication, when she weighed 300 pounds (approx. 136 kg).
“I made (2022 dramaTill), and a woman thought I was wearing a fat suit,”she saidin May 2024.
“I’m doing that wonderful shot that works for folks who need some help, and it’s been really good for me. It’s all the weight I’ve lost. I’ve lost almost two people.”
OPRAH SPECIAL EXPLORES WEIGHT-LOSS DRUGS: After Oprah Winfrey opened up about changing the conversation around obesity and shared her own struggles in the spotlight,#TheViewco-hosts discuss.https://t.co/cVclFZQmjApic.twitter.com/GUVfMPdW0T
— The View (@TheView)March 19, 2024
Image credits:TheView
Addressing the stigma surrounding weight loss, the EGOT winner said the “key is to stop judging everybody.”
“My weight has come and gone, and up and down, but it’s never been an issue for me because I don’t listen to what other people say about me so it has never been a problem,” she shared onThe Viewafter Oprah Winfrey’s specialShame, Blame and the Weight Loss Revolution.
“But I think it’s very hard for people to just know what a normal weight would be. Everyone has something to say but no one said, ‘How you doing?’ Because it involves so many other things.”
Expert reveals GLP-1 medications are “powerful weight-loss tools” but their long-term consequences need to be studied
Image credits:Haberdoedas/Unsplash
Harvard Healthnotesthat gastrointestinal symptoms, such as nausea, vomiting, and diarrhea, are the most common side effects of GLP-1 medications.
Less common but more serious side effects include pancreatitis, gastroparesis, bowel obstruction, and gallstone attacks and bile duct blockage.
Areesha Moiz, who conducted astudywith over 15,000 participants to evaluate Ozempic’s efficacy in weight loss treatment, concluded that GLP-1 agonists are “powerful weight-loss tools, though their long-term impacts are still being explored.” The medication led to weight loss of up to 14% after 16 months.
“This has gone too far,” one netizen said about the stars’ alleged use of Ozempic
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