Netizens have been keenly aware of therapid changesthe drug is known for after several celebrities confessed to its use last year, and they’ve been accusing any star of drastically losing weight after taking it ever since.

HighlightsAccording to netizens, many stars looked ‘gaunt’ at the 2025 Golden Globes, fueling Ozempic use rumors.Experts warn extreme weight loss makes celebrities look older, not better.Netizens express concern over stars' health, citing muscle loss and potential long term damage.

The 2025 edition of theGolden Globeswas no different. With the event putting extra pressure on stars to look perfect, many showed up with much leaner figures, immediately setting off alarms.

“I would not be surprised if most of the celebs at the Golden Globes were using GLP-1 to look their best for the show,” a dietician said in an interview with theDaily Mail. “It is extremely effective for weight loss, even if you are already not overweight.”

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Several starswere accusedof using Ozempic after appearing “suspiciously gaunt” at the 2025 Golden Globes red carpet

“Stunning weight loss transformations of a celebrity at the Golden Globes, showcasing elegant outfits and glamour.

Image credits:Amy Sussman / CBS Photo Archive

TopHollywoodstars such as Selena Gomez, Demi Moore, Nicole Kidman, Cynthia Erivo, and Ariana Grande were among those rumored to have turned to semaglutide, mostly known for its brand names Ozempic, Wegovy, and Mounjaro.

Their slimmer featurescome as apart of atrendthat glorifies more defined features, including thinner arms, sharper collarbones, and smaller cheeks. For experts, thetelltalesigns ofSemaglutideusage are the speed with which the changes occur.

Actress at Golden Globes, showcasing stunning weight loss transformation in elegant gowns.

Image credits:Mike Marsland / Axelle/Bauer-Griffin

Thesetransformationsusually result in the person looking slimmerbutwithout the muscle tone and firmness associated with a slower, less drastic approach to weight loss via diet and exercise.

Speaking with the outlet, plastic surgeon Dr. Dennis Schimpf refused to give the stars the benefit of the doubt, explaining that the lack of fat and looser skin present in actresses like Demi Moore and Nicole Kidmanwerelikelythe result ofusing Ozempic.

“The collarbones are very prominent, with no visible fat. That’s a clear signshemay have used a GLP-1 medication,” he said about Moore.

Instead of helping celebrities look better, experts warn that extreme weight loss causes the opposite, as the body loses the necessary fat to look young and healthy

“Person in floral dress at CMA Awards, stunning weight loss transformation at the Golden Globes in evening gown.

Image credits:Leah Puttkammer / Amy Sussman

For Dr. Schimpf, the two stars who better exemplified the dangers ofextreme weight losswere Cynthia Erivo and Ariana Grande, the main actresses of Disney’sWicked.

“The subcutaneous fat that normally smooths out the bone is kind of lost, so it collapses,” he said when looking at their pictures, with both women’s ribcages and collarbones sticking out from underneath their skin.

Schimpf explained how losing excess fat benefits most people aesthetically butactuallymakes themlook worsepast a certain point.

Celebrities at the Golden Globes showcasing stunning weight loss transformations in elegant dresses.

Image credits:Kevin Mazur / Amy Sussman

Fans went from being impressedto worried about the stars’ health, with many believing the trendto begetting out of control.

“People will trade their health to drop five or 10 pounds. When people are of average or even underweight, and they choose to use these medications, itdefinitelytakes a toll on their health,” one reader said.

“They may never know the consequences of their actions until later, and then it will be too late.”

Ozempic was initially designed to fight diabetes but became a commercial sensation for its appetite-reduction properties

Weight loss transformations showcased at the Golden Globes with two images of a woman in different outfits.

Image credits:Robino Salvatore /Jeff Kravitz

ActressKathy Bateswas among the attendants who showcased one of the most impressive transformations. Bates has been open about her weight loss journey, admitting to using the drug for its original, intended purpose: fighting diabetes.

Semaglutidewas initially designedto help patients improve their glycemic control. But in March 2024, the US Food and Drug Administration expanded the indication of the peptide to help obese people lose weight and reduce the risk of cardiovascular incidents.

Stunning weight loss transformations highlighted at the Golden Globes event.

Image credits:Jason LaVeris / Dan Doperalski/GG2025

It comes with a host ofside effects, which include nausea, diarrhea, vomiting, constipation, abdominal pain, headache, fatigue, indigestion/heartburn, and dizziness, among others.

The drug has become sosought afterthat Ozempic’s manufacturer, Novo Nordisk, has become Europe’s most valuable company, with a market value that exceeds that of its home country.

Celebrities show off weight loss transformations at the Golden Globes, stunning fans with their looks.

Image credits:kyliejenner

“People are missing a bigger problem. Whilst these celebrities have lost weight, they have also lost significant muscle mass,” one user stated. “It’s not a good look unless you prefer to look older than your years.”

“Ms. Erivo looked especially awful. Yes, many of the stars, including Nic and Demi, are too skinny. It’s quite nuts,” another said.

“I hope Cynthia regains her former healthy appearance because this really does her no favors.”

“You actually need some body fat to help fight infections. Your body takes energy from fat cells to boost immunity,” a reader explained. “People who go on these drugs and carry no fat are actually risking their health more than they know.”

“Kathy was the only one that needed the meds. The rest did it for vanity and are playing a very, very dangerous game. It’s madness.”

“Vanity is their curse.” Netizens worried about the long-term effects that using the drug will have on celebrities

Comment by Barbara Babcock on weight loss transformations: “There’s always a down side to a quick fix.

“Comment on Golden Globes weight loss transformations: ‘It’s a real crisis.'

“Comment by Ryan Salazar: ‘Vanity is their curse’, reacting to Golden Globes weight loss transformations.

Comment by Rob Reddy on weight loss transformations: “The difference between earning it, and taking shortcuts.

Lindie Faber commenting on weight loss transformations discussion.

“Comment on weight loss transformations at Golden Globes, stating they go too far.

Comment from Carole Cross Gilbert about weight loss transformations.

Fan comments on weight loss transformations, mentioning Ozempic humorously linked to a zombie apocalypse.

Text message discussing difficulty obtaining diabetes medication.

Comment on stunning weight loss transformations at the Golden Globes, expressing surprise.

Comment about stunning weight loss transformations at the Golden Globes suggesting dramatic changes.

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